Basic shake flask-based microorganism culture provides the lowest cost of entry, but lacks the feedback and bioprocess understanding provided from fully-fledged bioreactor systems with parameter control and multiple sensors.
The SBI DOTS platform allows for information gathering capability to be built back in at a lower cost. Most notably via Biomass sensors. The system can also allow for additional workflows such as biomass-based feeding strategies, e.g. for growth optimisation or yield improvement.